The Looney Tunes Show: Sylvester is sleeping on the ledge outside the office of Dr. Jekyll (whom we see in his office drinking the potion that turns him into a monster). Sylvester wakes up and chases the birds off the ledge. Tweety flies by and Sylvester chases him into Jekyll's lab. Tweety hides in the Hyde formula and becomes a giant Tweety monster terrorizing Sylvester. When Tweety returns to normal, the resumes the chase, always being caught with Tweety in a tight situation when the little bird reverts to "Mr. Hyde" size.

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